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Yes, I took it for several days and developed an annoying headache/feeling. It did not, at all, improve cognitive function. In my case it impaired it.

YMMV of course.

I've had far better luck with fish oil (Omega-3 supplements), taken every morning with earl grey tea. The fish oil helps me concentrate, while the tea releases caffeine more slowly than coffee does, preventing jitteriness and extending its duration.



To make fish oil, you need fish that are low enough in the food chain to not have many PCBs. Fish oil is usually made from the menhaden fish (aka the alewife fish), which used to be plentiful all around the Atlantic coastline of the US, feeding on algae. With all those fish turned into fish oil pellets, there are massive algae blooms, and the food chain's getting disrupted.

See http://www.ethicurean.com/2009/03/23/menhaden/ and http://motherjones.com/environment/2006/03/ill-take-menhaden


Thanks for that! Any recommendations on alternatives? I find other sources of Omega3 (flax seed) to be not as good unfortunately...


Fish oil helps my mood too.

You may want to be make sure that the fish oil is molecularly distilled to minimize your exposure to mercury and PCBs.


Yes, very good point, the brand I get does do that (Nature Made Liquid Softgels Odorless 1200mg).



Thanks for the link!

I'd certainly believe it. The amount of toxins man has put into the ocean is mind-boggling, so it's not a surprise if, even though they say on the damn bottle that they filter PCBs, that they're still there.

Edit: However, it looks like the one mentioned in the article is not the same one I use. The one in the article is Cod Liver oil. Still, that's no reason to assume the other one is safe, as this is quite a global problem.


Take a second look - it says Nature Made cod liver oil and odorless fish oil.

If only they said which ones DON'T have pcbs.


I've heard that the headache is due to a lack of choline, and that most people should be taking a choline supplement with their racetams.


I think I read that as well, but decided against it because the literature wasn't convincing enough (i.e., hearsay on forum posts), and I wasn't thrilled with ingesting, and possibly becoming dependent on so many substances.


Choline is a natural compound, you can get it by eating eggs. Most people take it as a supplement the same time with piracetam, you can buy them combined as well. It's definitely discussed in research as well as forums:

http://www.ncbi.nlm.nih.gov/pubmed/7301036 "The results of these studies demonstrate that the effects of combining choline and piracetam are quite different than those obtained with either drug alone"


Thanks for the pubmed link, didn't see that.

As far as choline goes, I eat an egg every day, and get my vitamins and minerals from fresh fruits, veggies and legumes. Just as you can obtain Vitamin-C or choline from a supplement, so too can you obtain them from natural sources. From what I understand of nutrition, the natural sources deliver the same nutrients in ways that our bodies can metabolize better.

I'm open to trying piracetam again, but it just doesn't seem all that significant to justify even the extra cost of buying it (and the supplements) and becoming dependent on it. If someone here actually does think it's worth it, I'd be very interested in hearing from you, provided you don't own a nootropics business.


One egg isn't going to do it. One egg gets you <200mg of choline, if I remember my research right, while you need more like >1000mg/1g to really see piracetam's effects. My DNB scores improved more with piracetam+choline than just piracetam: http://groups.google.com/group/brain-training/browse_thread/...




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