I just want to say that if you can't think of something substantial or meaningful to do, don't get discouraged. Trust me, I'm in your boat and don't know where to start. While I try to find that start, I'm also trying to focus on a startup I do believe in but I know is no charitable 'game-changer'. It's easier to have that bright idea or enforce some charitable influence once you have personal influence and resources (cough, cough..money). If you're in that position, you can make substantial difference much easier (and yes, you don't necessarily need those things either, but they do help)